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What is NEMO?
NEMO (X-linked NFkB Essential Modifier Deficiency), is a very rare and severe immune disorder which means one can't fight off germs. There currently are only a small number of NEMO survivors in the country and 60 worldwide.
NEMO is the name of a gene that regulates functions of the immune system. NEMO is like a "master switch" that is found on the cells of the human body and regulates signals between the cell membrane and the cell nucleus. NEMO is expressed in almost all tissue cells. If NEMO is not present life is not possible. NEMO stands for Nuclear Factor Kappa B Essential Modulator, which is a protein used for communication between the membrane and the nucleus. A bone marrow transplant replaces the faulty immune system and missing NEMO protein with a normal and healthy immune system. How's that for a simple explanation?